Since the late 19th and early 20th centuries, scientists were able to discover things like Langerhans islets, insulin mechanism of action, and the pathophysiology of Diabetes mellitus,this is why people are often familiar with insulin for its endocrine properties. These events are considered an “, important milestone in the history of medicine”,(1). . . .

The academic community, such as researchers, editors, and scholars relies on knowledge exchange and the spreading of innovative research. 1-3 For this community, the publication of their papers in a reputable journal is evidence of the quality and influence of their study. One vital step in this journey is receiving the first impact factor for a journal. The presence of an impact factor improves the visibility of journals among researchers, organizations, decision-makers, and policy-makers...

A uniformly convergent numerical scheme is developed for solving a singularly perturbed parabolic turning point problem. The properties of continuous solutions and the bounds of the derivatives are discussed. Due to the presence of a small parameter as a multiple of the diffusion coefficient, it causes computational difficulty when applying classical numerical methods. As a result, the scheme is formulated using the Crank-Nicolson method in the temporal discretization and an exponentially fitted finite difference method in the space on a uniform mesh. The existence of a unique discrete solution is guaranteed by the comparison principle. The stability and convergence analysis of the method are investigated. Two numerical examples are considered to validate the applicability of the scheme. The numerical results are displayed in tables and graphs to support the theoretical findings. The scheme converges uniformly with order one in space and two in time.

The rapid development of knowledge on healthy nutrition, and hygiene practices, as well as the advent of antibiotics and vaccines, has led to increased life expectancy in the recent century. The extended lifespan has brought new challenges for healthcare professionals, including the management of chronic degenerative diseases, malignancies, and autoimmune disorders. Advanced therapeutic medicinal products (ATMPs) have emerged as a promising frontier alongside conventional therapeutic modalities, offering innovative solutions through cell-based therapies, gene therapy, and tissue engineering. Recent years have witnessed remarkable advancements in regenerative medicine and the launching of innovative ATMPs. Numerous ATMPs have been registered and approved by regulatory agencies for the management of different diseases in 2023. The approval of groundbreaking therapies around the world has made 2023 an exceptional year. Novel ATMPs and the development of artificial intelligence (AI) in 2023 will pave the way for the integration of ATMPs and advanced technologies in personalized medicine, early diagnosis, and targeted treatments.